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Slovenska pediatrija 2015; 22: 224-239

https://doi.org/



Review article

THROMBOTIC MICROANGIOPATHY

T. Kersnik Levart
Klinični oddelek za nefrologijo, Pediatrična klinika, Univerzitetni klinični center Ljubljana, Ljubljana, Slovenija

Abstract

In this review, the author initially defines thrombotic microangiopathy (TMA). TMA can present clinically either as the haemolytic uraemic syndrome (HUS) or as thrombotic thrombocytopenic purpura (TTP). The pathophysiology, classification and clinical manifestations of each clinical entity are presented separately, as well as the relevant diagnostic work-up, treatment and prognosis.

Key words: thrombotic microangiopathy, haemolytic uraemic syndrome, thrombotic thrombocytopenic purpura, complement, children.


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