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Slovenska pediatrija 2016; 23: 288-295

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Review article


A. Zorman
Otroški oddelek, Splošna bolnišnica Celje, Celje, Slovenija

K. Meštrović-Popovič
Otroški oddelek, Splošna bolnišnica Celje, Celje, Slovenija

J. Vande Walle
Enota za pediatrično nefrologijo, Univerzitetna bolnišnica Ghent, Belgija

A. Meglič
Klinični oddelek za nefrologijo, Pediatrična klinika, Univerzitetni Klinični center Ljubljana, Ljubljana, Slovenija


Monosymptomatic enuresis is defined as intermittent bedwetting while asleep in a child older than 5 years, who does not have any daytime urinary dysfunction. The pathophysiology of enuresis is complex, the crucial pathogenic mechanisms being nocturnal polyuria, an increased arousal threshold and detrusor overactivity. Comorbid conditions (e.g., constipation and neuropsychiatric disorders) play an important role and can decrease the chance of successful therapy. In most cases, monosymptomatic enuresis can be effectively managed by education, including advice on drinking, eating and proper toilet habits, and the prescription of appropriate medication. Desmopressin and alarm treatment are considered to be equivalent first-line management.

Key words: enuresis, monosymptomatic, pathogenesis, management.